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Appendix 2: Curriculum Vitae

Personal Information
Name: John J. Pippin, M.D., F A.C.C.
Date of birth: January 7, 1950
Place of birth: Brookline, Massachusetts
Education
1971 A.B. (European History), Harvard College
Cambridge, Massachusetts
1980 M.D., University of Massachusetts Medical School
Worcester, Massachusetts
Postdoctoral Training
Internship and Residency
1980-81 Intern in Medicine
New England Deaconess Hospital, Boston, Massachusetts
1981-83 Resident in Medicine
New England Deaconess Hospital, Boston, Massachusetts
1983-84 Chief Medical Resident
New England Deaconess Hospital, Boston, Massachusetts
Fellowships
1984-86 Fellow in Cardiovascular Disease
New England Deaconess Hospital, Boston, Massachusetts
1986-87 Research Fellow in Nuclear Cardiology
University of Texas Southwestern Medical Center and Parkland Memorial Hospital, Dallas, Texas
Licensures and Certifications
1981 Massachusetts License, Registration No. 48194
1983 American Board of Internal Medicine, Certification No. 92336
1987 ABIM Certification, Cardiovascular Disease
1987 Virginia License, Registration No. 41616
1990 Authorized User of Radiopharmaceuticals
(Nuclear Regulatory Commission Certification)
1991 Oklahoma License, Registration No.
1997 Nuclear Cardiology Certification
Certification Board of Nuclear Cardiology
1998 Texas License, Registration No. K4984
Academic Appointments
1980-83 Clinical Fellow in Medicine
Harvard Medical School, Boston, Massachusetts
1983-86 Instructor in Medicine
Harvard Medical School, Boston, Massachusetts
1987-91 Assistant Professor of Medicine and Radiology
Medical College of Virginia, Richmond, Virginia
1993-97 Clinical Associate Professor of Medicine
University of Oklahoma Health Sciences Center
Oklahoma City Oklahoma (Tulsa campus)
Administrative Appointments (Clinical and Research)
1987-91 Director, Cardiovascular Stress Laboratories
Medical College of Virginia, Richmond, Virginia
1987-91 Co-Director, Nuclear Cardiology
Medical College of Virginia, Richmond, Virginia
1989-91 Director, Cardiology Fellowship Program
Medical College of Virginia, Richmond, Virginia
1989-91 Research Peer Review Committee
American Heart Association, Virginia Affiliate
1991-97 Medical Director, Nuclear Cardiology
Hillcrest Medical Center, Tulsa, Oklahoma
1994-97 Founding Director, Cardiovascular Assessment Center
William H. Bell Heart & Lung Institute
Hillcrest Medical Center, Tulsa, Oklahoma
1995-97 Founding Director, James D. Harvey Center for Cardiovascular Research
William H. Bell Heart & Lung Institute
Hillcrest Medical Center, Tulsa, Oklahoma
1995-97 Chairman, Institutional Review Board
Hillcrest Medical Center, Tulsa, Oklahoma
1995-97 Member, Institutional Review Board
University of Oklahoma Health Sciences Center, Tulsa, Oklahoma
1998-2004 Founding Director, Cardiovascular Medicine Department
Cooper Clinic, Dallas, Texas
2003-04 Founding Director, Medical Imaging Division
Cooper Clinic, Dallas, Texas
Administrative Appointments (Non-clinical)
1989-91 Coursemaster, M II Cardiovascular Medicine
Medical College of Virginia, Richmond, Virginia
1989-91 Internal Medicine Intern Selection Committee
Medical College of Virginia, Richmond, Virginia
1991-97 Medical Director, Tulsa Run, Tulsa, Oklahoma
1992-94 Infection Control Committee
Hillcrest Medical Center, Tulsa, Oklahoma
1992-96 Patient Advisory (Bioethics) Committee
Hillcrest Medical Center, Tulsa, Oklahoma
1994-96 Member, Physician Advisory Committee
Hillcrest Medical Center, Tulsa, Oklahoma
1994-96 Member, Board of Directors
Partnership Health Organization
Hillcrest Medical Center/Physician PHO
Hospital Staff Appointments
1980-86 New England Deaconess Hospital, Boston, Massachusetts
1987-91 Medical College of Virginia Hospital, Richmond, Virginia
1987-91 McGuire Veterans Administration Medical Center, Richmond, Virginia
1991-97 Hillcrest Medical Center, Tulsa, Oklahoma
1991-97 St. John Medical Center, Tulsa, Oklahoma
1994-97 St. Francis Hospital, Tulsa, Oklahoma
Professional Memberships
American College of Cardiology, Fellow
Texas Chapter, American College of Cardiology
American Society of Nuclear Cardiology, Founding Fellow
Texas Medical Association
Dallas County Medical Society
American Society of Hypertension
Awards and Honours
1967 National Merit Semifinalist
1979 Alpha Omega Alpha Medical Honor Society
University of Massachusetts Medical School
1981 James L. Tullis Award, New England Deaconess Hospital
Boston, Massachusett
1985 Invited Speaker and Panelist
American College of Cardiology Extramural Conference
New York, New York
1986-91 Clinician-Scientist Award
American Heart Association
1989 Invited Speaker, Society of Nuclear Medicine
Mideastern Chapter Annual Conference
Charlottesville, Virginia
1989 Cardiology Professor of the Year (Fellows' Award)
Medical College of Virginia, Richmond, Virginia
1990 Cardiology Professor of the Year (Fellows' Award)
Medical College of Virginia, Richmond, Virginia
1990 Cardiology Professor of the Year (Students' Award)
Medical College of Virginia, Richmond, Virginia
1996 Invited Speaker and Panelist
NIH National Human Subjects Protection Workshop
Oklahoma City Oklahoma
1997 Invited Speaker and Panelist
Society of Nuclear Medicine
Southwestern Chapter Annual Conference
New Orleans, Louisiana
1997- currentWho's Who in Medicine and Healthcare
Who's Who in Science and Engineering
Who's Who in America
Who's Who in the World

Bibliography

Books and Monograph Chapters

  1. Kosinski EJ, Pippin JJ. Preoperative evaluation of the diabetic patient. In: Kozak GP editor. Management of Diabetic Foot Problems. Philadelphia: WB Saunders 1984:133-43.
  2. Kahn JK, Pippin JJ, Corbett JR. New radionuclide agents for cardiac imaging: description and application. In: Wolfe CL, editor. Cardiology Clinics, 7(3): Cardiac Imaging. Philadelphia: WB Saunders 1989:589-605

Published Articles

  1. Pippin JJ. Breast cancer: epidemiology for the practicing physician. Worcester Medical News, May 6, 1979:13-8.
  2. Pippin JJ. Breast cancer: screening modalities, results and recommendations. Worcester Medical News, July 8, 1979:10-2.
  3. Pippin JJ. Breast cancer: the benefits and risks of mammography and breast self-examination. Worcester Medical News, September 10, 1979:16-9.
  4. Jansen DE, Pippin JJ, Hansen C, Henderson E, Kulkarni P Ugolini V, Corbett JR. Use of radioactive iodine-labeled fatty acids for myocardial imaging. Am J Card Imaging 1987;1:132-44.
  5. Hansen CL, Corbett JR, Pippin JJ, Jansen DE, Kulkarni PV, Ugolini V, Henderson E, Akers M, Buja LM, Parkey RW, Willerson JT Iodine-123 phenylpentadecanoic acid and single photon emission computed tomography in identifying left ventricular regional metabolic abnormalities in patients with coronary heart disease: comparison with thallium-201 myocardial tomography. J Am Coll Cardiol 1988;12:78-87.
  6. Henderson EB, Kahn JK, Corbett JR, Jansen DE, Pippin JJ, Kulkarni P Ugolini V, Akers MS, Hansen C, Buja LM, Parkey RW, Willerson JT Abnormal I-123 metaiodobenzylguanidine myocardial washout and distribution may reflect myocardial adrenergic derangement in patients with congestive cardiomyopathy. Circulation 1988;78:1192-9.
  7. Zarich S, Leonardi H, Pippin J, Tuthill J, Lewis S. Patent ductus arteriosus in the elderly. Chest 1988;94:1103-5.
  8. Kahn JK, Pippin JJ, Akers MS, Corbett JR. Estimation of jeopardized left ventricular myocardium in symptomatic and silent ischemia as determined by iodine-123 phenylpentadecanoic acid rotational tomography. Am J Cardiol 1989;63:540-4.
  9. Kahn JK, Carry MM, McGhie I, Pippin JJ, Akers MS, Corbett JR. Quantitation of postexercise lung thallium-201 uptake during single photon emission computed tomography. J Nucl Med 1989;30:288-94.
  10. Lane SE, Lewis SM, Pippin JJ, Kosinski EJ, Campbell D, Nesto RW, Hill T. Predictive value of quantitative dipyridamole thallium scintigraphy in assessing cardiovascular risk after vascular surgery in diabetes mellitus. Am J Cardiol 1989;64:1275-9.
  11. Quint RI, Rehr RB, Pippin JJ, Tatum JL. Effect of variation in heart size on quantitative thallium SPECT. Angiology 1991;42:734-40.
  12. Pippin JJ, Jansen DE, Henderson EB, Hansen CL, Ugolini V, Kahn JK, Kulkarni PV, Corbett JR. Myocardial fatty acid utilization at various workloads in normal volunteers: iodine-123 phenylpentadecanoic acid and single photon emission computed tomography to investigate myocardial metabolism. Am J Card Imaging 1992;6:99-108.
  13. Arrowood JA, Kline J, Simpson PM, Quigg RJ, Pippin JJ, Nixon JV Mohanty PK. Modulation of the QT interval: effects of graded exercise and reflex cardiovascular stimulation. J Appl Physiol 1993;75:2217-23.
  14. Warner MF, Pippin JJ, DiSciascio G, Paulsen WH, Arrowood JA, Tatum JL, Goudreau E, Vetrovec GW. Assessment of thallium scintigraphy and echocardiography during dobutamine infusion for the detection of coronary artery disease. Cathet Cardiovasc Diagn 1993;29:122-7.
  15. Verani MS, Taillefer R, Iskandrian AE, Mahmarian JJ, He ZX, Orlandi C, for the Multicenter IPPA Viability Trial Investigators. ___I-IPPA SPECT for the prediction of enhanced left ventricular function after coronary bypass graft surgery J Nucl Med 2000;41:1299-1307.
  16. Mitchell TL, Pippin JJ, Devers SM, Kimball TE, Cannaday JJ, Gibbons LW, Cooper KH. Age and sex based nomograms from coronary artery calcium scores as determined by electron beam computed tomography. Am J Cardiol 2000;87:453-6.
  17. Mitchell TL, Pippin JJ, Devers SM, Kimball TE, Gibbons LW, Cooper LL, Gonzalez-Dunn V Cooper KH. Incidental detection of preclinical renal tumors with electron beam computed tomography: report of 26 consecutive operated patients. J Comput Assist Tomogr 2000;24:843-5.
  18. LaMonte MJ, FitzGerald SJ, Church TS, Barlow CE, Radford NB, Levine BD, Pippin JJ, Gibbons LW, Blair SN, Nichaman MZ. Coronary artery calcium score and coronary heart disease events in a large cohort of asymptomatic men and women. Am J Epidemiol 2005; 162:1-9.
  19. Pippin JJ. PLoS takes a step backward. PLoS Medicine 2005;2(8):e278.

Published Abstracts

  1. Naggar CZ, Pippin JJ, Forgacs P Infective endocarditis: a changing disease. Chest 1984;86:316.
  2. Pippin JJ, Phillips RT, Lane SE, Perper E, Campbell D, Hill T, Lewis SM, Kosinski EJ. Dipyridamole thallium predicts complications in diabetics undergoing peripheral vascular surgery. J Am Coll Cardiol 1987;9:69A.
  3. Hansen CL, Jansen DE, Corbett JR, Ugolini V, Pippin JJ, Henderson E, Kulkarni P Buja LM, Parkey RW, Willerson JT Increased sensitivity of I-123 phenylpentadecanoic acid in the identification of exercise-induced myocardial ischemia. J Am Coll Cardiol 1987;9:25A.
  4. Pippin JJ, Jansen DE, Henderson EB, Corbett JR, van den Berg E, Schmitz J, Dehmer G, Kulkarni PV. I-123 phenylpentadecanoic acid imaging for the assessment of myocardial metabolic dysfunction before and after percutaneous transluminal coronary angioplasty. Clin Res 1987;35:314A.
  5. Henderson EB, Corbett JR, Jansen DE, Pippin JJ, Ugolini V Kulkarni PV, Hansen CL, Willerson JT. Noninvasive detection of abnormal myocardial catecholamine distribution in patients with congestive cardiomyopathy Clin Res 1987;35:286A.
  6. Pippin JJ, Jansen DE, Henderson EB, Corbett JR, van den Berg E, Schmitz J,Dehmer G, Kulkarni PV, Buja LM, Parkey RW, Willerson JT. Single-photon emission computed tomography utilizing I-123 phenylpentade canoic acid to assess myocardial fatty acid metabolism before and after percutaneous transluminal coronary angioplasty. J Nucl Med 1987;28:1084.
  7. Henderson EB, Jansen DE, Willerson JT, Pippin JJ, Ugolini V, Kulkarni PV, Hansen CL, Corbett JR. The myocardial imaging characteristics of I-123 metaiodobenzyl guanidine in patients with congestive cardiomyopathy and normals. J Nucl Med 1987;28:1084.
  8. Hansen CL, Corbett JR, Kulkarni P Ugolini V, Jansen DE, Pippin JJ, Henderson G, Buja LM, Parkey RW, Willerson JT Alterations in left ventricular fatty acid clearance in patients with acute myocardial infarction. J Nucl Med 1987;28:1084.
  9. Corbett JR, Henderson EB, Akers MS, Pippin JJ, van den Berg EK, Kulkarni PV, Jansen DE. Gated tomography with technetium-99m RP-30A in patients with myocardial infarcts: assessment of myocardial perfusion and function. Circulation 1987;76:IV-217.
  10. Pippin J, Corbett J, Henderson E, van den Berg E, Dehmer G, Schmitz J, Kulkarni P Jansen D. Serial assessment of myocardial fatty acid utilization in patients undergoing coronary angioplasty. Circulation 1987;76:IV-371.
  11. Pippin J, Corbett J, Jansen D, Henderson E, Hansen C, Ugolini V, van den Berg E, Dehmer G, Schmitz J, Kulkarni P Willerson J. Comparison of I-123 phenylpentadecanoic acid and thallium-201 tomographic imaging for the detection of coronary artery stenoses. Circulation 1987;76:IV-508.
  12. Lane SE, Pippin JJ, Lewis SM, Kosinski EJ, Campbell D, Hill T, Wheeler H. Prediction of cardiovascular risk in diabetic vascular surgery requires quantitative dipyridamole thallium scintigraphy J Am Coll Cardiol 1988;11:185A.
  13. Kahn JK, Henderson EB, Akers MS, Jansen DE, Pippin JJ, Kulkarni P Willerson JT, Corbett JR. Prediction of reversibility of perfusion defects with a single post-exercise technetium-99m RP-30A gated tomographic image: the role of residual systolic thickening. J Am Coll Cardiol 1988;11:31A.
  14. Kahn JK, Henderson EB, Akers MS, Jansen DE, Pippin JJ, Kulkarni P Corbett JR. Gated and ungated tomographic perfusion imaging with technetium-99m RP-30A: comparison with T1-201 tomography in coronary artery disease. J Am Coll Cardiol 1988;11:32A.
  15. Pippin JJ, Jansen DE, Henderson EB, Hansen C, Ugolini V, Kulkarni P Corbett JR. Workload-related variability of myocardial fatty acid utilization in normal volunteers.Clin Res 1988;36:307A.
  16. Kahn JK, Pippin JJ, Akers MS, Corbett JR. Assessment of myocardium at risk in silent ischemia: evaluation by I-123 phenylpentadecanoic acid and single photon emission computed tomographic (SPECT) imaging. Clin Res 1988;36:287A.
  17. Pippin JJ, Jansen DE, Henderson EB, Hansen C, Ugolini V Kulkarni PV Corbett JR. SPECT demonstration of workload and sex-related variability of myocardial fatty acid utilization in normals. J Nucl Med 1988;29:841.
  18. Kahn JK, Pippin JJ, Corbett JR. Do isolated abnormalities of T1-201 clearance during single photon emission computed tomography (SPECT) improve the assessment of significant coronary artery disease? J Nucl Med 1988;29:948.
  19. Pippin JJ, Romhilt DW, Rehr RB, Quint RI, Tatum JL. Effects of sex and method of stress upon myocardial thallium distribution, using single photon emission computed tomography. Clin Res 1989;37:7A.
  20. Pippin JJ, Tatum JL, Rehr RB, Quint RI, Romhilt DW. Supine infusion protocol for dipyridamole thallium imaging: hemodynamic responses and myocardial thallium uptake in normal volunteers. Clin Res 1989;37:7A.
  21. Kline J, Arrowood J, Pippin J, Roy V, Nixon JV, Paulsen W. Effects of dipyridamole infusion on Doppler echocardiographic indices of left ventricular filling in normals. Clin Res 1989;37:5A.
  22. Pippin JJ, Romhilt DW, Quint RI, Lees GS, Tatum JL. Predictive value of ST segment depression for reversibility on dipyridamole thallium imaging in patients with normal and abnormal electrocardiograms. J Nucl Med 1990;31:733.
  23. Pippin JJ, Tatum JL, Quint RI, Lees GS, Romhilt DW. Effect of pentoxifylline upon hemodynamic responses and thallium sensitivity with dipyridamole thallium imaging in peripheral vascular disease patients. J Nucl Med 1990;31:734
  24. Kline J, Arrowood J, Pippin J, Roy V, Hess M, Nixon JV. Effect of exercise on the QT interval after cardiac transplantation: hormonal vs. neural influences. Clin Res 1990;38:253A.
  25. Schmedtje JF, Eckberg DL, Nixon JV, Pippin JJ, Taylor AA, Varghese A. Hemodynamic consequences of cardiovascular deconditioning: functional effects. Circulation 1990;82:III-694.
  26. Arrowood J, McLane S, Roy V, Quigg R, Pippin J, Nixon JV. QT interval shortening with exercise is preserved after cardiac transplantation. J Am Coll Cardiol 1991;17:60A.
  27. Warner MF, Pippin JJ, Arrowood JA, Paulsen WHJ, Tatum JL, Goudreau E, Vetrovec GW. Dobutamine stress thallium and echocardiography for the detection of coronary artery disease. J Am Coll Cardiol 1992;19:312A.
  28. Pippin JJ, Durham J, Payne TD, Brodie MA. Stress and redistribution gated SPECT thallium imaging for detection of coronary artery disease: angiographic correlation. Clin Nucl Med 1994;19:263.
  29. Pippin JJ, Payne TD, Brodie MA, Durham J. Comparison of single detector and dual detector gated SPECT thallium imaging for simultaneous myocardial perfusion and functional assessment. Clin Nucl Med 1994;19:266.
  30. Payne TD, Pippin JJ, Branstetter CJ, Brodie MA, Devers SM, Durham SJ. Determination of left ventricular ejection fraction from gated SPECT thallium imaging: pilot study. Clin Nucl Med 1995;20:89.
  31. Pippin JJ, Durham SJ, Devers SM, Payne TD, Branstetter CJ, Brodie MA, Bagwill ML, Holdman YL. Diagnostic accuracy of gated SPECT thallium imaging: correlation with coronary angiography. Clin Nucl Med 1995;20:90.
  32. Pippin JJ, Payne TD, Devers SM, Durham SJ, Branstetter CJ, Brodie MA, Holdman YL,Bagwill ML. Comparative evaluation of exercise and pharmacological gated SPECT thallium images. Clin Nucl Med 1995;20:90.
  33. Devers SM, Pippin JJ, Payne TD, Carr CM, Branstetter CJ, Ross AD, Durham SJ. Dobutamine-mediated septal reversibility in gated dobutamine thallium imaging. Clin Nucl Med 1996;21:172.
  34. Payne TD, Pippin JJ, Branstetter CJ, Ross AD, Devers SM, Carr CM, Durham SJ. Left ventricular ejection fraction from gated SPECT thallium imaging: comparison with RNA and contrast ventriculography. Clin Nucl Med 1996;21:172.
  35. Pippin JJ, Durham SJ, Devers SM, Payne TD, Branstetter CJ, Brodie MA, Ross AD, Carr CM. Summary description of a clinically comprehensive method for noninvasive assessment of coronary artery disease: gated SPECT thallium imaging. Clin Nucl Med 1996;21:172.
  36. Mahmarian JJ, Taillefer R, Pippin JJ, Iskandrian AS, Borer JS, Filipchuk NG, Williams KA, Orlandi C, He Z-X, Verani MS. Improvement in left ventricular ejection fraction and cardiac volumes following coronary artery bypass surgery in patients with depressed left ventricular function: a prospective study J Nucl Med 1996;37:93P.
  37. Taillefer R, Iskandrian A, Verani M, Orlandi C, Davies G, Borer JA, Pippin J. Observer variability in myocardial viability assessment with I-123-IPPA: results from the multicenter IPPA study. J Nucl Med 1996;37:184P.
  38. Pippin JJ, Payne TD, Nemec JJ, Branstetter CJ, Ross AD, Devers SM, Carr CM, Durham SJ. Left ventricular ejection fraction from gated SPECT thallium imaging: comparable to RNA and superior to cardiac cath. J Am Coll Cardiol 1997;29:262A.
  39. Ross AD, Payne TD, Branstetter CJ, Devers SM, Carr CM, Durham SJ, Nemec JJ, Pippin JJ. Comparative evaluation of gated SPECT thallium cardiac imaging using standard and shortened acquisition protocols. Clin Nucl Med 1997;22:204.
  40. Payne TD, Pippin JJ, Nemec JJ, Ross AD, Branstetter CJ, Devers SM, Carr CM, Durham SJ. Assessment of the incidence and correlates of upward creep during gated SPECT exercise thallium cardiac imaging. Clin Nucl Med 1997;22:202.
  41. Branstetter CJ, Payne TD, Pippin JJ, Nemec JJ, Ross AD, Devers SM, Carr CM, Durham SJ. Determination of delay required to permit SPECT thallium myocardial perfusion imaging after NaI-131 thyroid ablation. Clin Nucl Med 1997;22:203.
  42. Carr CM, Pippin JJ, Devers SM, Durham SJ, Payne TD, Branstetter CJ, Ross AD, Nemec JJ. Conversion of gated SPECT thallium cardiac imaging results into same day cardiac catheterization: a feasibility study Clin Nucl Med 1997;22:203.
  43. Pippin JJ, Durham SJ, Devers SM, Payne TD, Branstetter CJ, Brodie MA,Ross AD, Carr CM, Nemec JJ. Maximizing diagnostic and prognostic cost effectiveness for coronary artery disease: gated SPECT thallium imaging. J Nucl Med 1997;38:164P.
  44. Pippin JJ, Devers SM, Buckner DJ, Weilbacher DC, Kettles MA. The ST hump sign: a reliable indicator for false positive electrocardiographic response during treadmill exercise. Circulation 2000;102:II-394

Manuscripts in Preparation

  1. Pippin JJ, Devers SM, Whitehead RY Buckner DJ, Weilbacher DC, Kettles MA: The ST hump sign: a reliable indicator for false positive electrocardiographic response during treadmill exercise testing.
  2. Pippin JJ, Devers SM, Henderson YL, Zavala E III, Buckner DJ. Comparison of peak exercise and immediate postexercise blood pressures during treadmill exercise testing: results and clinical implications.

Revised: September 2005

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